Myasthenia Gravis in Pregnancy

With myasthenia gravis in pregnancy, the pregnant woman may require respiratory support during labor, since myasthenia gravis is an autoimmune disease, in which antibodies are produced that attack certain structures of the muscles responsible for its control, causing muscle weakness.

In addition, myasthenia gravis in pregnancy may cause neonatal myasthenia, which is characterized by muscle weakness in the baby, as the antibodies from the mother that circulate in the blood can pass to the fetus through the placenta.

However, although the antibodies that cause this disease cross the placenta, only 20% of newborns born to mothers with myasthenia gravis in pregnancy present the disease at birth and, when they do present it, it tends to disappear a few days or weeks after birth, because maternal antibodies eventually disappear and the newborn does not produce antibodies of this type.